Patient Related Risk Factors for Coronary Stent Thrombosis – Single Center Experience

Dzan Horozic¹, Azra Durak-Nalbantic¹, Mirad Hujdur¹, Adin Belet², Amir Redzepovic¹, Omer Jusic¹, Demir Bejtovic¹, Mesud Jamakovic¹ , Ediz Porovic¹, Rijad Jahic¹, Alden Begic¹, Alen Dzubur¹

1 Clinic for Heart, Blood Vessels, and Rheumatism, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina
2 Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Corresponding Author:
Dzan Horozic MD. Clinic for Heart, Blood Vessels, and Rheumatism, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina; E-mail: dzan_horozic@hotmail.com; Phone: +387 62 507-194; ORCID ID: 0009-0002-6426-5756

Cite this article: Horozic Dz, Durak-Nalbantic A, Hujdur M, Belet A, Redzepovic A, Jusic O, et al. Patient Related Risk Factors for Coronary Stent Thrombosis – Single Center Experience. Sar Med J 2025; 2(2):83-89. 10.70119/0035-25

Pages: 83 – 89 / Published online: 16 December 2025

Original submission: 19 July 2025; Revised submission: 29 August 2025; Accepted: 25 October 2025

Abstract

Introduction. Over the past decades, there has been a significant improvement in the quality of percutaneous coronary interventions (PCI). Despite constant scientific improvements, stent thrombosis (ST) remains one of the main complications of PCI. The goal of this study is to assess patient related risk factors for the development of ST in patients treated with PCI.
Methods. This retrospective, cross-sectional, single center study included 77 patients who were treated for ST in the period from January 2019 to December 2023. For every included patient with ST, 2 patients with previous PCI without confirmed ST were randomly assigned as a control group (n=154). Data were obtained by the search of electronic medical records database. For every patient, basic demographic and clinical data were obtained.
Results. According to the study, the percentage of patients with ST who had bare metal stents (BMS) was significantly higher (72.41%) than that of patients without ST (27.59%) (p<0,001). Stent diameter and length did not differ significantly between the groups (p=0.392 and p=0.095, respectively). Multivariate analysis has shown reduced left ventricular ejection fraction (LVEF), dyslipidemia and BMS stent placement to be independent predictors for development of ST in patients after PCI (Χ² (3,241) = 39.99, p<0.001). There was no significant difference in the distribution of type of P2Y12 inhibitor used after initial stent placement between patients with ST elevation and the control group (p=0.056).
Conclusion. Lower ejection fraction, presence of dyslipidemia and usage of BMS were identified as independent predictors of ST.

Keywords: Stent Thrombosis, Risk Factors, Prognosis.